Patient Information: SSRIs and Hot Weather

As temperatures rise during periods of warm weather or a heatwave, patients taking selective serotonin reuptake inhibitors (SSRIs) should take extra care to avoid becoming overheated or dehydrated.

Common SSRIs include sertraline, citalopram, escitalopram, fluoxetine and paroxetine.

Why is hot weather important?
SSRIs can affect the body’s ability to regulate temperature and may increase sweating in some people. This can make you more vulnerable to dehydration, heat exhaustion, dizziness and feeling unusually hot or unwell.

How can you stay safe?
• Drink fluids regularly unless you have been advised to restrict your fluid intake.
• Stay out of direct sunlight during the hottest part of the day (usually 11am–3pm).
• Wear lightweight, loose-fitting clothing.
• Keep your home cool by closing curtains or blinds in sunny rooms.
• Avoid excessive alcohol intake.
• Take regular breaks in cool or shaded environments if outdoors.

Symptoms to watch for
Seek medical advice if you develop persistent dizziness, severe headache, excessive thirst, nausea, vomiting, muscle cramps, marked weakness, confusion or disorientation.

Do NOT stop your antidepressant
Continue taking your SSRI as prescribed. Do not stop your medication suddenly without medical advice.

When to seek urgent medical attention
Seek urgent medical help if you experience a very high temperature, severe confusion or agitation, loss of consciousness, severe dehydration, or symptoms suggestive of serotonin syndrome.